Modification of N-glycosylation sites allows secretion of bacterial chondroitinase ABC from mammalian cells
نویسندگان
چکیده
منابع مشابه
Trafficking and processing of bacterial proteins by mammalian cells: Insights from chondroitinase ABC
BACKGROUND There is very little reported in the literature about the relationship between modifications of bacterial proteins and their secretion by mammalian cells that synthesize them. We previously reported that the secretion of the bacterial enzyme Chondroitinase ABC by mammalian cells requires the strategic removal of at least three N-glycosylation sites. The aim of this study was to deter...
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ژورنال
عنوان ژورنال: Journal of Biotechnology
سال: 2010
ISSN: 0168-1656
DOI: 10.1016/j.jbiotec.2009.11.002